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Care You Can Count On: Hospitals Serving the Upstate

  • March 20, 2026
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From nationally recognized medical centers to community hospitals rooted in compassionate care, the Upstate’s health care network is one of the region’s greatest strengths. Serving a rapidly growing population, hospitals across the area combine advanced technology, specialized services and a deeply personal approach, reflecting the same spirit of excellence and hospitality that define the region itself.

Bon Secours St. Francis Health System

BonSecours.com
This private not-for-profit health system boasts some of the highest patient-satisfaction ratings in the nation.

  • Three medical campuses
  • Two acute care hospitals
  • Emergency services
  • Outpatient surgery and therapy centers
  • Physicians network
  • Primary care and family medicine
  • Comprehensive heart-care program
  • Cancer care and oncology
  • Specialty facilities
  • Onsite chaplain and 24/7 pastoral support

AnMed Health

AnMedHealth.org
This comprehensive not-for-profit health system serves Upstate South Carolina and northeast Georgia and has 60 offices and facilities.

  • Four medical campuses
  • Two acute care hospitals
  • Level 2 trauma center
  • Emergency services
  • Behavioral health center
  • Women’s and children’s hospital
  • Rehabilitation hospital
  • Outpatient and diagnostic centers
  • Nuclear medicine exams
  • Specialty facilities
  • Physicians network
  • Walk-in clinics

Prisma Health – Upstate

PrismaHealth.org
This public not-for-profit academic health system is widely recognized as the state’s most comprehensive health care provider and is one of the Southeast’s leading medical facilities.

  • Eight medical campuses
  • Seven acute care hospitals
  • Level 1 trauma center
  • Children’s hospital
  • Psychiatric hospital
  • Rehabilitation hospital
  • Regional medical center
  • Community wellness center
  • Research and education facilities
  • Specialty centers
  • Physicians network

Novant Health

NovantHealth.org
This integrated, not-for-profit hospital system offers a full spectrum of services from urgent care treatment to specialists.

  • 6 urgent care facilities across the Upstate
  • Orthopedics and sports medicine
  • Head and neck reconstructive
  • An upcoming Patewood Drive medical campus will include a hospital, medical office building and outpatient services

Shriners Children’s Greenville

GreenvilleShrinersHospital.org
This 50-bed pediatric orthopedic hospital and research/teaching center provides comprehensive medical, surgical and rehabilitative care to children with orthopedic conditions, congenital anomalies, burns, spinal cord injuries and diseases of the neuromusculoskeletal system.

Spartanburg Regional

SpartanburgRegional.com
This integrated, not-for-profit health care delivery system has a reputation for technological excellence and provides care from birth through the senior years in six counties in North and South Carolina.

  • Research and teaching hospital
  • Five acute care hospitals
  • Level 1 trauma center
  • Emergency care
  • Cancer center and research institute
  • Skilled nursing and rehabilitation facilities
  • Outpatient and diagnostic centers
  • Urgent care
  • Physicians network
  • Specialty facilities
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