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Culture Crawl: Museums Worth the Stop

  • March 20, 2026
  • Claire Billingsley
Photo by Megan Fitzgerald
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From hands-on science exhibits and local history to bold art and unexpected finds, the Upstate’s museums invite you to explore, learn and be inspired.

Anderson County Museum
202 E. Greenville St., Anderson
AndersonCountyMuseum.sc.gov
This collection of artifacts is curated to spark interest and insight into the people and events that shaped Anderson.

Greenville County Museum of Art
420 College St., Greenville
GCMA.org
The South’s premier American art museum features the largest public collection of watercolors by American icon Andrew Wyeth, plus 40 works by Jasper Johns.

Greer Heritage Museum
106 S. Main St., Greer
greerheritage.com
This museum features exhibits of artifacts from Greer’s dynamic history, with interactive displays for kids. Special events include a popular series of ghost tours.

Hub City Railroad Museum
298 Magnolia St., Spartanburg
HubCityRRMuseum.org
Located in the historic Southern Railway Spartanburg Union Depot, this museum invites visitors to step back in time to learn about the origins of railroading in Spartanburg and the Upstate. Opportunities include learning how to become a telegrapher, ringing a locomotive bell and exploring a fully restored caboose.

Military History Center of the Carolinas
14 Airport Road Extension, Greenville
MilHCC.org
This space is dedicated to collecting and restoring military items. In addition to the museum itself, which has free entry, museum items are displayed at events throughout the year.

Museum & Gallery
1700 Wade Hampton Blvd., Greenville
BJUMG.org
The M&G features 105 Italian Baroque paintings among America’s largest collection of Old European Masters. It is currently open for private tours only.

Pickens County Museum of Art
307 Johnson St., Pickens
Co.Pickens.SC.US
This museum features a unique blend of local art and history exhibits. Items on display include a model of Fort Prince George, Hitler’s radio and a 19th century doctor’s field kit. The museum hosts two annual art shows each year and features work from local artists, too.

Shoeless Joe Jackson Museum & Baseball Library
356 Field St., Greenville
ShoelessJoeJackson.org
Visit the baseball legend’s home and see the many artifacts, photos and books that document Jackson’s place in baseball history.

Sigal Music Museum
516 Buncombe St., Greenville
SigalMusicMuseum.org
Sigal, the No. 3 best new museum in the country per USA Today, tells the diverse stories of musical instruments from across the globe.

Photo by Keith Muccilli Photography

Spartanburg Art Museum
200 E. St. John St., Spartanburg
SpartanburgArtMuseum.org
This regional museum promotes contemporary visual arts with a diverse range of exhibits and educational programs.

Spartanburg Regional History Museum
200 E. St. John St., Spartanburg
SpartanburgHistory.org
This museum reflects the area’s rich heritage from before European settlers to the present day. Collections showcase life, industry and cultural arts.

The Children’s Museums of the Upstate
300 College St., Greenville
130 Magnolia St., Spartanburg
TCMUpstate.org
These museums are Smithsonian affiliates that spark a passion for curiosity and learning through play. Greenville’s interactive exhibits and hands-on activities interest children of all ages; Spartanburg’s programming is designed for ages 5 and under.

The Galleries at First Presbyterian Church of Greenville
200 W. Washington St., Greenville
FirstPresGreenville.org/Art-Gallery
There are three levels of viewing space with exhibitions by local and internationally known artists including Makoto Fujimura.

Upcountry History Museum
540 Buncombe St., Greenville
UpcountryHistory.org
Explore the Upstate’s history within 43,000 square feet of interactive exhibits. Family Fun Days and Neighborhood Nights make it accessible for all.

Upstate Pinball & Arcade Museum
109A W. Trade St., Simpsonville
UpstateArcade.com
This fully playable museum houses classic arcade games from the ’80s and ’90s, as well as pinball machines from the ’70s through today.

World of Energy
at Duke Energy’s Oconee Nuclear Station
7812 Rochester Highway, Seneca
Duke-Energy.com
Come enjoy this engaging experience with educational exhibits about how energy works. There are educational video games and movies, too. Visitors are encouraged to pack a picnic and enjoy the views of scenic Lake Keowee.

  • Claire Billingsley
    Claire Billingsley
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