Hotels here offer more than a place to rest — each delivers style, comfort and prime access to the area’s thriving dining, arts and outdoor scenes. From charming boutique stays to sleek, modern favorites, here’s your guide to the best places to stay while exploring the Upstate.
AC Hotel Greenville
315 S. Main St., Greenville ACGreenville.com
Located in the heart of downtown Greenville, this hotel offers guests easy access to Main Street shops and restaurants. For on-site dining, check out the Spanish-Mediterranean tapas bar, Paloma.
AC Hotel Spartanburg
225 W. Main St., Spartanburg ACSpartanburg.com
Guests have access to a seasonal outdoor pool with cabanas and a gym with a Peloton bike. Dining options include breakfast at AC Kitchen, rooftop dining at Level 10, and drinks at the AC Lounge.
The Bleckley Inn
151 E. Church St., Anderson BleckleyInn.com
This historic property melds century-old details, including pinewood floors and exposed brick, with modern conveniences. There are on- and offsite spaces for events and meetings.
Aloft Greenville Downtown
5 N. Laurens St., Greenville AloftGreenvilleDowntown.com
Recharge in the gym or take a dip in the outdoor pool. Enjoy dinner and drinks at W XYZ Bar, the on-site rooftop restaurant that has live music on the weekends.
Courtyard by Marriott Greenville Downtown
50 W. Broad St., Greenville MarriottCourtyardGreenville.com
Located a short walk from the Peace Center and Falls Park, this convenient hotel is a great option for the traveler wanting to experience the best of downtown Greenville.
Embassy Suites by Hilton Greenville Downtown Riverplace
250 RiverPlace, Greenville https://www.hilton.com/en/hotels/gspgdes-embassy-suites-greenville-downtown-riverplace/
Overlooking the Reedy River and with easy access to the Prisma Health Swamp Rabbit trail, this hotel is the perfect place to begin exploring Greenville. Guests can enjoy the indoor saltwater pool and delicious meals at Ruth’s Chris Steakhouse, which is located above the hotel.
Grand Bohemian Lodge Greenville
44 E. Camperdown Way, Greenville Marriott.com/gspak
This luxury lodge provides guests with views of Falls Park and the city’s iconic Liberty Bridge. The signature Bohemian interiors and luxury amenities such as spa treatments will lead to a relaxing, memorable stay.
Hampton Inn & Suites Greenville-Downtown-RiverPlace
171 RiverPlace, Greenville HamptonInnandSuitesGreenville.com
Conveniently located among the city’s shops and restaurants, this hotel provides a complimentary breakfast, fitness-center access and pet-friendly rooms.
Homewood Suites Greenville Downtown
950 S. Main St., Greenville @Homewood.GreenvilleDowntown
Located by Fluor Field and a short walk from Gather GVL, amenities at this hotel include a seasonal outdoor pool, a fitness facility and complimentary breakfast.
Hotel Domestique
10 Road of Vines, Travelers Rest HotelDomestique.com
Cyclists will enjoy renting custom bikes and traversing owner George Hincapie’s cycling routes. The hotel’s interior is inspired by Hincapie’s European travels. Amenities include an infrared sauna, a saltwater pool and dining at Restaurant 17.
Hotel Hartness
120 Halston Ave., Greenville HotelHartness.com
Named Travel & Leisure’s 2024 World’s Best Resort in South Carolina, this hotel offers luxurious accommodations, exquisite meals at Patterson Kitchen + Bar, and rejuvenating spa treatments at Spa H.
Hyatt Place Greenville Downtown
128 E. Broad St., Greenville HyattPlaceGreenvilleDowntown.com
Whether you’re returning from a show at Greenville’s Bon Secours Wellness Arena (a short walk away) or a day of seeing the city’s sites, this hotel offers a great place to relax at the indoor pool or grab a bite at the The Placery, the restaurant located at the lobby bar.
Hyatt Regency Greenville
220 N. Main St., Greenville GreenvilleHyatt.com
Enjoy a handcrafted cocktail in this hotel’s signature bright, airy atrium, which features a 40-foot artisan chandelier. The space includes the Grand Regency Ballroom, which is the largest hotel ballroom in the Upstate.
Lakeside Lodge Clemson
13500 Clemson Blvd., Seneca LakesideLodgeClemson.com
With views of Clemson University’s Death Valley stadium across Lake Hartwell, its own miniature football field and tailgating accommodations including access to a full bar and delectable food, this hotel is a football lover’s paradise.
Residence Inn/Springhill Suites Greenville Downtown
200 E. Washington St., Greenville Marriott.com/gspgs / Marriott.com/gspgr
Here you will find a 24-hour gym, a beautiful, seasonal outdoor pool/sun deck, and enjoy complimentary breakfast. Experience the scratch-made cuisine and handcrafted cocktails at the on-site restaurant, Oak & Honey.
The Shepherd Hotel
110 Sloan St., Clemson ShepherdHotels.com
This boutique hotel holds hospitality at its core. Through a partnership with Clemson University’s LIFE program, The Shepherd offers students and adults with intellectual disabilities the opportunity to train and work at the hotel and its restaurant.
The Westin Poinsett, Greenville
120 S. Main St., Greenville WestinPoinsettGreenville.com
This AAA four-diamond hotel is a historic gem in downtown Greenville. Unwind with a cocktail while listening to music at The Piano Lounge, have a meal at the family-friendly Spoonbread Restaurant and stretch out in one of the hotel’s signature “Heavenly Beds.”
